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A generic organ based ontology system, applied to vertebrate heart anatomy, development and physiology
Bertens, Laura M. F. ; Slob, Joris ; Verbeek, Fons J.
Journal of Integrative Bioinformatics - JIB (ISSN 1613-4516)
We present a novel approach to modelling biological information using ontologies. The system interlinks three ontologies, comprising anatomical, developmental and taxonomical information, and includes instances of structures for different species. The framework is constructed for comparative analyses in the field of evolutionary development. We have applied the approach to the vertebrate heart and present four case studies of the functionality of the system, focusing on cross-species comparisons, developmental studies, physiological studies and 3D visualisation.
||Faculty of Technology, Research Groups in Informatics
||Data processing, computer science, computer systems