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From MIN model to ordinary differential equations
Yartseva, A. ; Devillers, R. ; Klaudel, H. ; Kepes, F.
Journal of Integrative Bioinformatics - JIB (ISSN 1613-4516)
Biological interaction networks can be modeled using the Modular Interaction Network (MIN) formalism, which provides an intermediary modeling level between the biological and mathematical ones. MIN focuses on a simple but structured and versatile representation of biological knowledge, without targeting a particular analysis or simulation technique. In this paper, we propose a translation procedure which, starting from a MIN specification of a biological system, generates its representation in ordinary differential equations (ODEs) allowing to study the dynamics of the system. The translation is illustrated on a classical benchmark: the lambda phage genetic switch.
||Faculty of Technology, Research Groups in Informatics
||Data processing, computer science, computer systems
Yartseva, A. ; Devillers, R. ; Klaudel, H. ; Kepes, F. (2007
) From MIN model to ordinary differential equations.
Journal of Integrative Bioinformatics - JIB (ISSN 1613-4516), 4(3), 2007. Special Issue: 4th Integrative Bioinformatics Workshop, Gent, Belgium