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An Unusal Distribution of 6-nt Sequences Near The Transcription Start Site

Mitra, Chanchal K. ; Milanesi, Luciano

Journal of Integrative Bioinformatics - JIB (ISSN 1613-4516)



Abstract:
A new look at the transcription start is presented in which we can see transcription factors binding to both sides of the TSS as an essential requirement. Naturally the factor binding to the downstream region must be removed so that transcription process can continue. The presence of a number of distinct transcription factors also can be used to explain selective activation of various genes. The transcription start site by itself plays only a minor role in the whole process. We also suggest that mutations close to the TSS on the coding side can be fatal even if preserves the codon table.


Beteiligte Einrichtung: Technische Fakultät, Arbeitsgruppen der Informatik
DDC-Sachgruppe: Datenverarbeitung, Informatik

Zitat-Vorschlag:
Mitra, Chanchal K. ; Milanesi, Luciano  (2008)  An Unusal Distribution of 6-nt Sequences Near The Transcription Start Site. Journal of Integrative Bioinformatics - JIB (ISSN 1613-4516), 5(2), 2008

Online-Journal: http://journal.imbio.de/index.php?paper_id=103
URL: http://biecoll.ub.uni-bielefeld.de/volltexte/2008/297



 Fragen und Anregungen an: publikationsdienste.ub@uni-bielefeld.de
 Letzte Änderung: 15.2.2011
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